Japanese Ministry of Health,Labour and Welfare shows that the estimated number of all patients with any anxiety disorders is more than ten million, while the number of all depressive patients is about six million. Thus, anxiety disorders are very important in daily clinical situation of psychiatry.
 Recently,DSM-5 draft posted online（http://www.dsm5.org）.Many of the disorders that were previously listed in the anxiety disorders chapter in DSM-IV have been distributed throughout this chapter as well as separate chapters on obsessive-compulsive and related disorders and trauma-and stressor-related disorders.
 As for panic disorder that was one of the new concepts of psychiatric disorder in DSMIII, there are some changes in the criteria,for instance subcategory according to with/without agoraphobia are discontinued since agoraphobia is proposed to be a codable disorder in DSM-5.
 In this paper, we will review the history and pathogenesis of panic disorder and the relationships between DSM and ICD,and then discuss the present and future of panic disorder viewed in DSM-5 draft.