Psychiatric disorders are more commonly seen in general medical inpatient settings than in community settings. These inpatients are at particular risk for general medical and psychiatric treatment resistance,increased complications of disease,high health care service use, and disability. It is time to focus on improving the consultation-liaison psychiatry service system through care coordination strategies. In order to deliver high quality, effective, and efficient integrated care for medically complex patients, the appropriate assessment of health risks, resulting in coordinated care and effective communication,is the first step toward establishing a systematic approach in general hospital settings.