Epilepsy is known to be comorbid with a variety of psychiatric symptoms such as depression, anxiety, hallucinations, delusions, emotional lability, and irritability. These psychiatric symptoms are considered to be related to antiepileptic drugs. Currently, many new antiepileptic drugs are widely used in Japan, and antiepileptic drug treatments have greatly changed. However, it was reported that some new antiepileptic drugs can induce or exacerbate psychiatric symptoms in patients with epilepsy. In Japan, although the number of psychiatrists who specialize in epileptology is decreasing, and opportunities to treat psychiatric symptoms comorbid with epilepsy is increasing in general psychiatric settings. Therefore, knowledge of psychiatric symptoms comorbid with epilepsy, especially psychiatric symptoms related to antiepileptic drugs, is essential for psychiatrists.
<Author's abstract>
Antiepileptic Drugs and Psychiatric Symptoms
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, NHO
Psychiatria et Neurologia Japonica
121: 19-23, 2019
<Keywords:antiepileptic drug, psychiatric symptom, depression, psychosis, irritability>