This paper discusses the maladjustment reaction of adults with autism spectrum disorders such as Asperger syndrome to a working environment or university setting, from the viewpoint of a psychiatrist seeing them in areas of occupational and college mental health.
 The author is in charge of a day care program for company workers, called“The Return‒to‒Work Support Course”, at a mental clinic. A total of 176 patients attended the program and most of them were originally diagnosed with depression and/or adjustment disorder. The author noted that five of them showed some traits of developmental disorder. They initially had been capable specialists at work, but started showing mental and psychosocial dysfunction as they received promotions and became team leaders or managers. It seems that changes in their work environment involving their superiors, co‒workers, the organization, etc., easily affected their work performance and triggered their maladjustment, and finally caused their leave of absence.
 The author also works in a university student counseling room, and noted that some students started to show maladjustment in the course of writing their graduation thesis or applying for jobs, although they previously had performed fairly well at university. They could not maintain good communication with thesis advisers, could not perform adequately during a group discussion at a job interview, or could not cope with personnel offices appropriately. After being interviewed, they were diagnosed with Asperger syndrome. 　　Not only child psychiatrists but all psychiatrists should have a sufficient knowledge of developmental disorders, and they need to be cautious when they diagnose patients and inform them.