Some investigations report that dosage amount and number of antipsychotics in Japan were higher than those in the other country. This problem was discussed as quality of psychiatric medication by “the conference of the future about psychiatric health, medicine and welfare”（Japanese ministry of health, labor and welfare; 2009）. The report of this conference said “In order to accelerate improvement to single dosage and loss in quantity, we should be grasped of the actual condition about the polypharmacy and extensive medication of antipsychotics for schizophrenic patients,and we should be discussed about the methods of information and evaluation”.
 But there is no evidence about the polypharmacy is good or bad,and no one knows actual condition about the Japanese antipsychotics medications. In order to answer this question, we are undergoing “the clinical study about safety and effective correction of polypharmacy and agent extensive medication of antipsychotics”.